The purpose of this systematic review was to. This study detected a higher rate of subclinical respiratory depression in patients in the ketamine group than the propofol group. The use of ketamine, propofol and their combination (ketofol) is in common practice, but there is currently no intravenous anesthetic agent that is ideal.
Drugs such as propofol and ketamine are used alone or in combination to provide sedation for medical procedures in children. More recent research has shown that ketamine may. In this article we attempt to describe the postulated benefits of using.
In terms of reducing the incidence of pip, ketamine is more effective than placebo (rr = 0.43, 95% ci = [0.34, 0.55], p < 0.00001), lidocaine (rr = 0.70, 95% ci = [0.55, 0.90],. Early research had stated that ketamine can cause a dangerous increase in intracranial. Both ketamine and propofol are powerful anesthetic and sedative drugs, but they work through different mechanisms and produce distinct effects. In this combination, propofol serves to provide sedation while ketamine serves to provide analgesia without increasing the respiratory depressant effects of propofol.
There was no difference in the rate of clinical. Brain injuries (tbi) (takeshita et al., 1972). Recently, ketofol, which is a combination of ketamine and propofol, has been increasingly used because the advantages and disadvantages of propofol and ketamine complement each other. Ketamine and propofol mixed in the same syringe (ketofol) is gaining interest as the agent of choice for procedural sedation and analgesia (psa), in hematological oncology.